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About THE PARIS TRANSPLANT GROUP

The Paris Transplant Group has been reaching further and deeper for the last 10 years on 3 main axes:
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worldwide collaborations
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multidisciplinary team covering solid organ transplantation
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gathering of data from various specialties (clinical, biological, immunological, pathological, -omics and biomarkers) within an organ specialty

Our Goal

The first step is to create an accurate landscape of the heterogeneity of a transplant's function, disease, activity, stage and response to therapy. From this heterogeneous landscape, we will:
  • address transplant phenotypes including pathophysiology across organs;
  • improve risk stratification;
  • reclassify disease state;
  • provide a new clinical decision support system (CDSS);
  • engineer a reporting system;
  • calibrate the read-outs to get real-time clinical meaning.

The second step will provide transplant clinicians with innovative and accessible tools for early prediction of individual risk of allograft rejection and transplant loss, offer them the possibility to personalize clinical management and treatment and improve transplant outcome. The final product is being developed as an integrated diagnostic system in the form of a diagnostic/prognostic score.

This will also set the stage for personalized transplant medicine by providing endpoints for clinical trials with insights in therapy and patient clinical management.

A cooperative group since 2008

The PTG has developed its network for more than a decade and is now proud and grateful to collaborate with more than 13 centres and hospitals in France, 12 centres in 6 countries in Europe, 14 centres in 4 countries in America on more than 30 different projects.

ACHIEVEMENTS IN PATIENT CARE

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Diagnosis:
  • Precision diagnosis
  • Gene expression
  • Disease heterogeneity
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Therapy efficacy:
  • Response to therapy
  • Personalized medicine
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Prognosis:
  • Risk stratification
  • Enrichment of trials

Read our RESULTS

Our AFFILIATED Medical centres

OUR AFFILIATED Academic Institutions

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