Category: Elodie Bailly

Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study

10/27/2021

For individuals with end-stage renal disease, kidney transplantation is the best treatment, in terms of quality and quantity of life and costs for society. Considering the organ shortage worldwide, the allograft failure is a real burden in chronic kidney disease, contributing to the growing number of the seven million individuals with end-stage renal disease. For these reasons, health agencies such as the Food and Drug Administation and the European Medicines Agency, have emphasized the need for developing a prediction model that would accurately predict the risk of allograft failure, which would allow clinicians to continuously enhance their prognostic judgements, and adapt the patient monitoring and management.

PTG at the ATC’s 2020 Virtual Congress

5/29/2020

Every year, the American Transplant Congress (ATC) gathers experts of organ transplantation from all over the world. For the 2020 edition, due to sanitary concerns and travel regulations, the in-person ATC initially planned in Philadelphia has been cancelled and replaced by a Virtual Congress. The event starts on 30 May 2020 for 3 days of live broadcasts.

The topic of ATC 2020 is “The Science of Tomorrow Starts Today” and covers the latest research in the field of transplantation. It showcases the research done in the industry too.

Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study

3/3/2020

The first universal algorithm for predicting the risk of kidney transplant loss, named iBox, has been developed, validated and just made public by teams from Europe and the US.

The iBox is designed for clinicians to personalize and improve patient follow-up. The iBox could also accelerate the development of new immunosuppressive treatments by reducing the duration of clinical trials and defining a valid surrogate endpoint.

Chronic kidney disease affects 1 out of 10 people worldwide and is steadily increasing. When it reaches end-stage renal disease and endangers the lives of patients, dialysis or transplantation is required.

Paris Transplant Group at the SFT congress 2019

12/2/2019

The members of the Paris Transplant Group are present at the SFT congress which will take place from December 3, 2019 in Bordeaux, France.

Many lectures by the Paris Transplant Group are planned to present the ongoing research to the French transplant community. The presentations will cover:

The latest results of clinical research, including the TRANSFORM study carried out with Novartis,
Research on transplant prognosis for improved patient follow-up, including the iBox algorithm.
Advances made in understanding the mechanisms at work in the event of rejection or unsuccessful transplantation.

This research covers kidney, lung and other transplantation.

Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study

PTG at the ATC’s 2020 Virtual Congress

Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study

Paris Transplant Group at the SFT congress 2019

Paris Transplant Group

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