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Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study

10/27/2021

 
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For individuals with end-stage renal disease, kidney transplantation is the best treatment, in terms of quality and quantity of life and costs for society. Considering the organ shortage worldwide, the allograft failure is a real burden in chronic kidney disease, contributing to the growing number of the seven million individuals with end-stage renal disease. For these reasons, health agencies such as the Food and Drug Administation and the European Medicines Agency, have emphasized the need for developing a prediction model that would accurately predict the risk of allograft failure, which would allow clinicians to continuously enhance their prognostic judgements, and adapt the patient monitoring and management.

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PTG at ESOT 2021

8/24/2021

 
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From 29th August to 1st September 2021, the Paris Transplant Group joins the 20th edition of the European Society for Organ Transplantation’s (ESOT) biennial congress in Milano.
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Many members of the Paris Transplant Group are attending the event. Especially, do not miss the plenary presentation of Alexandre Loupy about “Fine-tuning endpoints in specific transplant settings”.

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Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the US

12/15/2020

 
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New research indicates that analyses of kidney biopsies from deceased donors don’t provide meaningful information beyond standard assessments of donor and recipient characteristics. In addition, the study revealed that relying on these analyses has prompted the discard of many potentially suitable organs for transplantation in the United States. The findings appear in JASN.

Despite a critical scarcity of organs available for transplantation, thousands of deceased donor kidneys are discarded each year in the United States. 


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PTG at the ATC’s 2020 Virtual Congress

5/29/2020

 
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Every year, the American Transplant Congress (ATC) gathers experts of organ transplantation from all over the world. For the 2020 edition, due to sanitary concerns and travel regulations, the in-person ATC initially planned in Philadelphia has been cancelled and replaced by a Virtual Congress. The event starts on 30 May 2020 for 3 days of live broadcasts.
The topic of ATC 2020 is “The Science of Tomorrow Starts Today” and covers the latest research in the field of transplantation. It showcases the research done in the industry too.

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Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study

3/3/2020

 
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The first universal algorithm for predicting the risk of kidney transplant loss, named iBox, has been developed, validated and just made public by teams from Europe and the US.

​The iBox is designed for clinicians to personalize and improve patient follow-up. The iBox could also accelerate the development of new immunosuppressive treatments by reducing the duration of clinical trials and defining a valid surrogate endpoint.
Chronic kidney disease affects 1 out of 10 people worldwide and is steadily increasing. When it reaches end-stage renal disease and endangers the lives of patients, dialysis or transplantation is required. ​

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Paris Transplant Group at the SFT congress 2019

12/2/2019

 
The members of the Paris Transplant Group are present at the SFT congress which will take place from December 3, 2019 in Bordeaux, France.
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Many lectures by the Paris Transplant Group are planned to present the ongoing research to the French transplant community. The presentations will cover:
  • The latest results of clinical research, including the TRANSFORM study carried out with Novartis,
  • Research on transplant prognosis for improved patient follow-up, including the iBox algorithm.
  • Advances made in understanding the mechanisms at work in the event of rejection or unsuccessful transplantation. 
This research covers kidney, lung and other transplantation.

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PTG awarded the ESOT StrongeR Together Pro Award

9/16/2019

 
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The team of the Paris Transplant Group has been awarded at the ESOT 2019 congress in Copenhagen for its many contribution in the field of transplantation. 

The Prize is given to a single Institution having submitted at least 5 abstracts for the event and granted with the best score. The Paris Transplant Group is very pleased to won this European award twice in a row. 

Check out the contribution submitted by the Group on the ESOT website: esotcongress.org.

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