PTG
  • Home
  • Research
    • PTG Research
    • iBox technology
    • Publications
    • Collaborations
    • Granted Projects
    • Awards
    • Database access
  • Platforms
    • Technical & Analytical Platforms
  • Team
    • Current team
    • PTG alumni
  • News & Media
    • Latest news
    • Photo and Video Gallery
    • PTG in the media
  • Job offers
  • About

Dynamic prediction of renal survival among deeply phenotyped kidney transplant recipients using artificial intelligence: an observational, international, multicohort study

10/27/2021

 
Picture
For individuals with end-stage renal disease, kidney transplantation is the best treatment, in terms of quality and quantity of life and costs for society. Considering the organ shortage worldwide, the allograft failure is a real burden in chronic kidney disease, contributing to the growing number of the seven million individuals with end-stage renal disease. For these reasons, health agencies such as the Food and Drug Administation and the European Medicines Agency, have emphasized the need for developing a prediction model that would accurately predict the risk of allograft failure, which would allow clinicians to continuously enhance their prognostic judgements, and adapt the patient monitoring and management.

Read More

COVID-19-related medical research: a meta-research and critical appraisal

1/12/2021

 
Picture
As with many fields, science has been put to the test by the coronavirus pandemic. An international team of researchers, led by French scientists, has demonstrated novel scientific practices around Covid-19. Under the pressure of the number of cases and the urgent need to understand the virus, many research groups have shared results, sometimes to the expense of high scientific standards.

During the first wave of the Covid-19 epidemic, medical research saw a historic number of studies on the coronavirus published in a short period of time. An international consortium of experts in medical methodology undertook the major challenge of evaluating the Covid-19 research during this first wave.

Read More

A. Loupy, Awarded GENEWIZ Digital Spatial Profiler Grant

1/7/2021

 
Picture
Leading global genomics service provider, GENEWIZ, a Brooks Life Sciences Company, announced today that Alexandre Loupy, MD, Ph.D., Professor of Nephrology and Epidemiology at Necker Hospital, Paris, and Director of the Paris Transplant Group at Inserm, France, has been awarded the GENEWIZ Digital Spatial Profiler Grant. Pr. Loupy will be provided digital spatial profiling services on the NanoString Technologies® GeoMx™ platform for his study investigating the spatial immune response during allograft rejection.

Read More

Assessment of the Utility of Kidney Histology as a Basis for Discarding Organs in the US

12/15/2020

 
Picture
New research indicates that analyses of kidney biopsies from deceased donors don’t provide meaningful information beyond standard assessments of donor and recipient characteristics. In addition, the study revealed that relying on these analyses has prompted the discard of many potentially suitable organs for transplantation in the United States. The findings appear in JASN.

Despite a critical scarcity of organs available for transplantation, thousands of deceased donor kidneys are discarded each year in the United States. 


Read More

Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study

3/3/2020

 
Picture
The first universal algorithm for predicting the risk of kidney transplant loss, named iBox, has been developed, validated and just made public by teams from Europe and the US.

​The iBox is designed for clinicians to personalize and improve patient follow-up. The iBox could also accelerate the development of new immunosuppressive treatments by reducing the duration of clinical trials and defining a valid surrogate endpoint.
Chronic kidney disease affects 1 out of 10 people worldwide and is steadily increasing. When it reaches end-stage renal disease and endangers the lives of patients, dialysis or transplantation is required. ​

Read More

Archetype Analysis Identifies Distinct Profiles in Renal Transplant Recipients with Transplant Glomerulopathy Associated with Allograft Survival

3/14/2019

 
Picture
New research conducted by the Paris Translational Research Center for Organ Transplantation team could help clinicians determine which patients will have a disease that usually occurs after a kidney transplant and which are at high risk of transplant failure. The results are published today in the prestigious Journal of the American Society of Nephrology (JASN).

Transplant glomerulopathy was first described and characterized 50 years ago. It is a disease associated with the loss of a kidney transplant and common after a transplant. It affects the functional units (i. e. glomeruli) of the transplanted kidney. There is currently no treatment for this heterogeneous disease.

Read More

Timing of anti-donor antibody responses affects the survival of kidney transplants

3/2/2017

 
Picture
Kidney rejection initiated by antibodies that were present before transplantation is linked with a better outcome that rejection due to antibodies that arise after transplantation
New research provides insights on transplant recipients’ antibody responses against donor kidneys and how the timing of those responses can have important implications. The findings appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
Picture

Read More

    Paris Transplant Group

    Our global aim is to accelerate the translation of immunological and gene expression discoveries into the clinical field by filling the gap between basic science and applied biomedical researches.

    CATEGORIES

    Awards
    Events
    Job offers
    Press Releases
    Publications

    See also

    Press coverage
    Video and ​Picture gallery

    ALl

    All
    Alexandre Loupy
    Antoine Bouquegneau
    Antoine Durrbach
    Antoine Roux
    Awards
    Blaise Robin
    Carmen Lefaucheur
    Charlotte Debiais
    Charlotte Loheac
    Christophe Legendre
    Daniel Yoo
    Dany Anglicheau
    Denis Glotz
    Denis Viglietti
    Dina Zielinski
    Elodie Bailly
    Events
    Gillian Divard
    Guillaume Bonnet
    Guillaume Coutance
    Huanxi Zhang
    Jean Luc Taupin
    Jean Paul Duong Van Huyen
    Jean Philippe Empana
    Jessy Dagobert
    Job
    Juliette Gueguen
    Kevin Louis
    Marc Raynaud
    Marie-Cécile Bories
    Marion Rabant
    Maud Racape
    Michel Delahousse
    Olivier Aubert
    Pascal Leprince
    Patrick Bruneval
    Peter Reese
    Press Releases
    Publications
    Shaida Varnous
    Valentin Goutaudier
    Xavier Jouven
    Yassine Bouatou
    Zeynep Demir

    Archives

    October 2021
    September 2021
    August 2021
    July 2021
    February 2021
    January 2021
    December 2020
    November 2020
    October 2020
    September 2020
    August 2020
    July 2020
    May 2020
    March 2020
    January 2020
    December 2019
    October 2019
    September 2019
    August 2019
    June 2019
    May 2019
    March 2019
    February 2019
    December 2018
    September 2018
    May 2018
    February 2018
    January 2018
    December 2017
    November 2017
    October 2017
    September 2017
    June 2017
    May 2017
    April 2017
    March 2017
    February 2017
    January 2017
    December 2016
    November 2016
    June 2016
    April 2016
    October 2015
    June 2015
    August 2014
    January 2014
    September 2013
    January 2013
    June 2011
    August 2010
    May 2009

    RSS Feed

Paris Transplant Group

About PTG
PTG Team
​​Careers at PTG
​Latest News
​
Awards
Video and Picture Gallery

PTG in the Press
​Contact us

Research

iBox technology
PTG Research
PTG Publications
Covid-related research 🔓

Platforms

Technical platforms

Partnerships

Research collaborations
​Database access
​

Search

LEGAL NOTICE AND PRIVACY POLICY
© COPYRIGHT 2022. ALL RIGHTS RESERVED.

 LABS EXPLORER for the PARIS TRANSPLANT GROUP.
  • Home
  • Research
    • PTG Research
    • iBox technology
    • Publications
    • Collaborations
    • Granted Projects
    • Awards
    • Database access
  • Platforms
    • Technical & Analytical Platforms
  • Team
    • Current team
    • PTG alumni
  • News & Media
    • Latest news
    • Photo and Video Gallery
    • PTG in the media
  • Job offers
  • About